A Metabolite of ‘Carbromal’

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Bioassay of carbromal for possible carcinogenicity.

A bioassay for the possible carcinogenicity of carbromal was conducted using Fischer 344 rats and B6C3F1 mice. Carbromal was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each species with the exception of 49 low dose male mice and high dose female mice. Twenty animals of each sex and species were placed on test as controls. The high an...

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ژورنال

عنوان ژورنال: Nature

سال: 1960

ISSN: 0028-0836,1476-4687

DOI: 10.1038/188058a0